ILC07 Automated Diffusion System
PermeGear’s ILC07 Automated Diffusion System incorporates In-Line Cells, a peristaltic pump, a fraction collector, and a heater/circulator into a versatile system for analyzing diffusion over time. Collection vials are at the option of the user, racks for 20ml 28mm diameter scintillation vials are provided. Adapters are available to allow the use of many different vials popular with many HPLC autosamplers. Because of the varied requirements of individual users, vials must be provided by the user, PermeGear will supply appropriate racks.
PermeGear’s ILC07 Automated Diffusion Systems are based on the continuous flow principle. A multi-channel peristaltic pump draws receptor solution from a reservoir through a distribution manifold and sends it to the In-Line Cells. The cell temperatures are adjusted by a heater/circulator that pumps water through the Cell Warmer in which the In-Line Cells are located. After filling the receptor chambers of the cells and purging the system of bubbles, the subject compound is then placed in the donor chambers of the cells. From that time, the fluid is collected in the vials of the fraction collector at user set time intervals. The vials are taken for analysis manually after the sampling time has elapsed.
The ILC07 components are properly arranged when the fraction collector (FC33) is on a bench top with the heater/circulator to its right. The peristaltic pump and 2-liter glass reservoir are located on the stainless steel shelf attached to the back of the FC33. The peristaltic pump is placed so the cassettes are centered left to right with respect to the FC33. The 2-liter reservoir bottle is located to the right of the peristaltic pump and the distribution manifold is directly behind the pump.
-1- ILC07-MANUAL-5/17-01
Note: All references made to direction
in this manual, unless otherwise specified, assume that the equipment is being viewed from the normal operating position with the displays of the fraction collector and heater/circulator facing the user. The peristaltic pump is placed on the shelf behind the FC33 so that the controls are on the right end and the cassettes are on the left.
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